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DeCS
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Descriptor English:
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Methyl CpG Binding Domain
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Descriptor Spanish:
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dominio de unión a metil-CpG
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Descriptor Portuguese:
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Domínio de Ligação a CpG Metilada
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Synonyms English:
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Methyl CpG DNA Binding Domain
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Tree Number:
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G02.111.570.820.709.275.750.438
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Definition English:
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A protein domain of about 70 amino acids in length that folds into a sandwich structure consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in eukaryotic DNA BINDING PROTEINS. |
See Related English:
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DNA Methylation
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56741
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Unique Identifier:
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D000070593
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Occurrence in VHL:
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Similar:
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DeCS
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